Traditionally, the EECs were classified by the peptide they secrete, although more recently, application of RNA sequencing has led us to know that a single EEC can produce multiple hormones within an individual, and different hormonal promoters may be active at different times (90, 91) The distribution of the different EECs across the gastrointestinal tract that is generally accepted is: Stomach: P/D1 cells (ghrelin), D cells (somatostatin), G cells (gastrin), and ECL cells (histamine)
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Historical precedent from adalimumab (Humira) and insulin glargine (Lantus) shows 30% to 50% price drops within 12 months of biosimilar entry when 3+ competitors launch
And also, we saw each other two years in a row at Dave Asprey's biohacking conference, which was so amazing
Most people taking GLP-1 medications report finally feeling normal for the first time in a long time
For a general deficiency, many protocols start with 100 mcg injections daily or every other day for the first week