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Microencapsulated bitter compounds (from Gentiana lutea) reduce daily energy intakes in humans
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Cardiovasc Ther (2012) 30(3):e14655
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We start in the periphery with vagal, intestinofugal, and spinal sensory nerves and then progress through the brainstem up to the hypothalamus and finish at non-canonical brain feeding centers such as the zona incerta and lateral septum
These medications work synergistically with the altered anatomy from sleeve gastrectomy or gastric bypass, allowing patients to achieve the same degree of appetite calmness that they felt shortly after surgery
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