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Although there is strong evidence supporting the benefit of GLP-1RAs in populations with obesity, their efficacy in other populations of particular HF subtypes and specific cardiomyopathies is unclear
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Hikma generic (first FDA-approved generic): On December 23, 2024 , Hikma Pharmaceuticals received FDA approval for the first traditional generic liraglutide
Paradoxically, very low calcium diets can increase oxalate absorption and stone formation
Furthermore, this novel concept suggests that the GLP-1 analog could spare the pasireotide-induced decrease in endogenous GLP-1 concentrations and recover insulin secretion suppressed by pasireotide through GLP-1R-Gs activation counteracting the SSTRs-Gi axis
