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This reduction was not only accompanied by downregulation of endogenous mouse ApoE expression in the brain, but also decreased the levels of synaptic glutamate receptors, presynaptic protein -syn [89]
Autophagy and lysosomal dysfunction in diabetes and its complications
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The adoption of the PCPA-induced insomnia model in mice has enabled researchers to delve into the molecular mechanisms underlying sleep regulation ( GABA (Gamma-Aminobutyric Acid) primarily functions as an inhibitory neurotransmitter in the brain, promoting relaxation and sleep ( Materials and methods Secretory expression of the fusion peptides between Delta-sleep inducing peptides and cross the blood-brain barrier peptides (DSIP-CBBBP) from P
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