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Consistent with this, loss of the trisulfide bond sharply reduced SQORs thermal denaturation temperature from 66 C to 36.5 C (Figure 2 shows the crystal structure of human SQOR
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Introduce a fiber supplement if needed
To maximise the cardiovascular benefits of GLP-1 RAs at a population level, strategies can be used to improve tolerability, such as patient counselling, gradual dose escalation and the use of long-acting formulations [27]
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