Summary: GLP-1 medications do build up in your system until reaching a stable therapeutic level called steady state, typically within 3 days to 7 weeks depending on the specific drug
Importantly, no signals of drug-induced liver injury have emerged despite extensive real-world use, supporting the favorable hepatic safety profile of GLP-1 RAs [62]
Zhang, Z., Zhao, M., Wang, J., Ding, Y., Dai, X., & Li, Y
After a few days, the dose can be increased to around 0.5mg to 1mg per day
In fact, according to Andels own research, about 44% of members say they would switch jobs for GLP-1 coverage
We are seeing so many patients utilizing these drugs [that] we will see other complications during patient use that some would attribute to side effects of the medication, David I