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The delayed stomach emptying can lower LES pressure slightly, making it easier for stomach acid to reflux upward

While not listed as a likely side effect of semaglutide, some data have been presented showing a potential for acute pancreatitis

Not the panic version

Current Diabetes Reports, 19(11), 106

High cholesterol Early studies suggested that pharmacological doses of pantethine, a pantothenic acid derivative, might have a cholesterol-lowering effect (30, 31)

Saying "I have noticed my desire has changed since starting this medication, and I want to work through it with you" is infinitely more productive than silently withdrawing from intimacy and leaving a partner to wonder why