Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease
Specific concerns for Crohn's patients include: Nausea and vomiting : May exacerbate existing symptoms or lead to dehydration, particularly concerning in patients with active disease Diarrhea : Difficult to differentiate from Crohn's-related diarrhea, potentially delaying recognition of disease flares Abdominal pain : May mask or mimic Crohn's-related pain, complicating clinical assessment Reduced oral intake : Appetite suppression combined with nausea may worsen nutritional deficiencies common in IBD Additional FDA-labeled risks include: Acute gallbladder disease : Cholelithiasis and cholecystitis occur more frequently with semaglutide, particularly with rapid weight loss [12] [15] Acute kidney injury : Dehydration from gastrointestinal side effects may lead to kidney injury Pancreatitis : Patients should be monitored for severe, persistent abdominal pain, sometimes radiating to the back Rare but serious gastrointestinal adverse events reported in post-marketing surveillance include cases of bowel obstruction and ileus
Therefore, considering cardiorenal protective effects, no interaction was observed between baseline SGLT2i use and efpeglenatide
persistent heartburn may signal underlying gastrointestinal disorders that, if left unchecked, could lead to more serious health complications
Many patients continue improving their body composition, energy levels, and metabolic health even during temporary plateaus. Karla K
This process contributes to ATP production, which is how your cells store and release energy
