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The SURMOUNT-5 data on waist circumference is also clinically meaningful: research has shown that each 5-centimeter increase in waist circumference corresponds to a 7 to 9 percent increase in mortality risk, making the 5.4-centimeter additional reduction with tirzepatide a potentially significant benefit.1 That said, semaglutide remains highly effective and is still the right choice for many patients, depending on insurance coverage, cost, tolerance, and individual response
Temporary triglyceride elevation during rapid weight loss is uncommon but can occur as the body mobilizes stored fat
While these effects are much more modest than medication, they can still help improve fullness, support blood sugar control, and contribute to better metabolic health over time
The hunger simply is not there, or is so muted that it barely registers
I have a ton of muscle on me
M.Abd El-HaleimE
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