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All rights reserv Further changes in ammonia level and occurrence of obvious hepatic encephalopathy After 3 months of treatment, we recommended that the patients continue taking L-carnitine for as long as possible (up to 1 year)

Therefore, to investigate the influence of GST enzyme activity on busulfan metabolism, the empirical model developed was used as a base, with a dedicated compartment incorporated to dynamically quantify the relative amount of GSH available over time, based on theoretical mechanisms, as reported by Langenhorst et al

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