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These medications work with your bodys natural hormones to help regulate appetite, blood sugar, and digestion
Mechanism of action Sarah Spinler GLP-1 and glucose-dependent insulinotropic peptide (GIP) are incretin hormones that are released postprandially to increase insulin secretion and decrease glucagon secretion, ultimately lowering blood glucose
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The approval gives Ozempic (semaglutide) the broadest label in the class, coming after earlier approvals for type 2 diabetes itself and cardiovascular risk reduction in diabetics with known heart disease
Contrave may modestly increase blood pressure/heart rate Contrave has more contraindications, including seizure disorders, eating disorders, and opioid use Neither is a controlled substance, unlike phentermine Contrave costs less ($100-300/month vs $199-349/month for semaglutide) Both are FDA-approved for weight loss, though through different formulations How Each Medication Works Understanding the mechanisms explains why these medications produce different effects and suit different patients
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