Selenoprotein W is a glutathione-dependent antioxidant in vivo
Also, the male KO mice had an increased CYP1A2 (Part of the P450 enzyme family that are responsible for a large part of detoxification), however this wouldnt really explain the differences seen in Figure 2 (side-note: Ok, this last part was extremely geeky and I try to make this as mainstream as possible
GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) deliver remarkable weight loss but create a critical nutritional challenge: maintaining adequate protein intake
By The Numbers How Common Is GLP-1 Hair Loss
Bias was curtailed by allocation concealment, double blinding of participants, investigators, and laboratory staff, and an ITT analysis
It serves as a buffer for the acyl-CoA/CoA ratio, which is critical for normal cellular metabolism