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Occasionally, a small lump or slight irritation can occur at a subcutaneous injection site, which is usually just the liquid sitting in the tissue before its fully absorbed
Sun et al
If in hot and humid location, follow refrigerator desiccant instructions
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Otolaryngol Head Neck Surg 2025;172:134856
On top of that, the injectable form carries the same practical drawbacks as other injectable peptides: needles, sterile reconstitution, refrigeration, degradation after mixing, and the ongoing friction of maintaining a regular injection routine for benefits that build gradually over months
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