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Notably, FGF21 analogs have reduced insulin resistance or decreased liver fat in clinical trials 16,26

The remarkable commercial success of drugs like semaglutide and tirzepatide has created strong market momentum, driving significant investment in next-generation molecules and accelerating development cycles

Cancer 77 , 288298 (2025)

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Because semaglutide builds gradually in your system, early changes in body weight tend to be subtle

NTS2 is localized to many of the same brain regions as NTS1 (Mazella et al., 1996