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Key findings from the Phase 2 data included: Dose-dependent weight loss : Greater reductions in body weight were observed with higher doses, suggesting a clear pharmacological dose-response relationship

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Improvement in fibrosis was also assessed, showing a dose-dependent trend, with 34% of patients achieving at least a 1-stage improvement in fibrosis without MASH progression in the 6 mg group (vs

Another PCOS concern is endometrial cancer risk

Further competition comes from tirzepatide, approved by the FDA in 2022 and now sold under the Mounjaro/Zepbound brand name.