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Glutathione signaling helps control reactive oxygen species (ROS), which can damage the body and kill cells

Low risk (awareness only): dietary copper from food, moderate alcohol, L-carnosine at standard doses, free histidine supplements below 1,000 mg

Supraphysiologic dosages (higher amounts than the body can make or ingest through diet) MUST be achieved in order for melatonin to exert its antioxidant effect

This integrated approach addresses multiple factors affecting healing capacity

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10.1016/S1474-4422(17)30470-2 434 ThompsonR