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IgE-mediated food allergies have numerous symptoms, including systemic reactions (anaphylaxis), acute or chronic skin symptoms (urticaria, AD, angioedema), respiratory symptoms (asthma, rhinitis, laryngitis, ear inflammation), and gastrointestinal symptoms (abdominal pain, nausea, diarrhea, bloating, loss of appetite, vomiting) (174)

Fragile X syndrome (FXS) [327] is the most common mutation-based form of intellectual disability Fragile X syndrome (FXS) Its prevalence rate accounts for about 1 in 4000-5000 males and 1 in 6000-8000 females [328, 329]

R19.7, K52.9, A09, K58.0, K59.1, and K52.1 retain their FY 2025 definitions and Excludes1 structures

These might include additive, synergistic, or antagonistic effects that cannot be reliably predicted without dedicated pharmacokinetic and pharmacodynamic studies

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In practice, it seems better to tailor the choice to different patients, depending on the preference of the route of administration (oral vs injectable), the presence of intolerance or side-effects, and contraindications