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To view digital features for this article go to Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a class of incretin-based therapies for the treatment of type 2 diabetes (T2D), have been shown to be highly effective for both glycaemic control and weight loss, and are associated with a low risk of hypoglycaemia [1]

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It is also effective for post-inflammatory hyperpigmentation from acne, eczema, and psoriasis

4.1 Short chained fatty acids The ability of certain members of the GM, such as Faecalibacterium , Bifidobacteria and Lactobacilli (LeBlanc et al., 2017) to produce SCFAs is reported to be key to the interaction between the microbiota and the host, and according to Liu et al

That said, its important to know when discomfort crosses the line