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The PfGrx C32S/C88S (SSG)-dependent oxidation of roGFP2 WT or glutathionylation of both monothiol roGFP2 variants were accelerated at increasing glutaredoxin concentrations and followed pseudo-first-order kinetics (Fig
Arer and Duclaut
Preclinical study
The pro-oxidant antioxidant balance (PAB) did not differ between groups (4.6 12.8, p = 0.72)
In contrast, adult immunization of this mouse strain, which is prone to develop diabetes, failed to protect, so timing was central to protection
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