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If nausea is severe enough to prevent adequate nutrition, reduce both compounds to the last tolerated dose and extend the stabilization period before attempting re-escalation

Following each experiment, the cells were washed once with PBS (LPS solution CBP007B) and fixed with 10% formalin solution (Sigma HT501128-4L) for 10 min at room temperature

R., Luijten, M., Miyashima, S., Lenhard, M., Hashimoto, T., Narajima, K., Scheres, B., Heidstra, R., and Laux, T