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DSIP Reconstitution Math (10 mg vial) Vial 10 mg BAC water 2.0 mL Concentration 5.0 mg/mL (5,000 mcg/mL) 100 mcg draw 0.02 mL = 2 units 200 mcg draw 0.04 mL = 4 units 300 mcg draw 0.06 mL = 6 units Units shown are U-100 insulin-syringe units

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Taking into account the selective, dynamic and adaptive aspects of the bloodbrain interfaces together with inspiration from the domain of political philosophy [8], we believe that the notion of a border, rather than that of a barrier, better captures the properties of these interfaces