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Side Effects: Does the Route Change Tolerability
It is now established that dermal hair follicles provide a major source of stem cells used for dermal healing
Modifying the biological, chemical, and physical properties of these small molecules can improve their release rate, solubility, and stability, distribution, and metabolism in vivo
Considering the dose-dependent rise in side effects, it raises questions about the justifiability of higher doses
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These effects make IGF-1 a promising therapeutic approach for tendon injuries, which typically heal slowly and often result in inferior mechanical properties compared to uninjured tissue
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