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The ABC transporters ABCB1 (MDR1), ABCC1 (MRP1), and ABCC2 (MRP2) among others are involved in ATP-dependent efflux of drugs or drug-GS conjugates

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15, 16, D-CuP, ROS-responsive hydrogel matrix (G) and G/D-CuP demonstrated good biocompatibility

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[2] Without enough glutathione, the entire antioxidant system loses efficiency