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The enhanced potency and extended dosing interval of semaglutide mark a significant advancement in GLP-1 RA therapy for both glycemic and weight management
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This isn't a weakness
The renin-angiotensin-aldosterone system (RAAS) has a significant role in regulating blood pressure, blood volume, and response to alterations in renal or myocardial performance
Until those results are in, the recommendation is extrapolated from non-pharmacologic weight-loss literature plus 2024-2025 case reports of GLP-1 patients who lifted and held their lean mass [11]
In those taking semaglutide and receiving loop diuretics, their loop diuretics dose decreased by 17% after 52 weeks
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