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The clinical data does not show tolerance development in the way that some other medications lose effectiveness over time

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Psychiatry 21, 16961709

However, excess or chronic inflammation causes many adverse health effects including fatigue, joint pain, digestive issues, anxiety and increased risk of developing cancer, heart disease, diabetes, and Alzheimers in the future

[PMID: 38971269] PubMed record related to this compound for laboratory literature review

3 The metabolites of TCM drugs targeting ferroptosis for cancer therapy 3.1 Alkaloids Solasonine, a steroidal glycoalkaloid derived from Solanum nigrum L