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[10] [12] High doses of ascorbic acid can increase the absorption of iron from the gastrointestinal tract and may potentiate the effects of oral iron supplementation or exacerbate iron overload in susceptible individuals
Trial participants experienced different levels of % total body weight loss depending on the dose: Percentage of total body weight loss on retatrutide After 48 weeks , 83% of patients taking 12 mg lost at least 15% of their body weight , compared to just 2% of those who were on a placebo
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Discontinuation rates due to adverse events were 4.1% (4 mg), 6.9% (9 mg) and 11.3% (12 mg), compared to 4.9% with placebo
