Relative to comparators, the risk for any of the commonly used cardiovascular end points was estimated to be below 1.0, and for both MACE-4 and MACE-3 (myocardial infarction, stroke, and all-cause death), the upper bounds of the confidence interval calculated around the hazard ratio were decidedly 8.5 %
The small increase in heart rate (23 beats per minute on average) associated with Ozempic is generally not clinically significant for most patients and does not usually require treatment modification
Antioxidants & Redox Signaling, 23 (11), 985-997
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