Some health problems can make it hard for the body to take in vitamin B12
Kalayci F, Yigit M, Kalyoncu Arican GM, Gokdol MY, Tekin MY, Kalayci OK, Celebier K, Kacar D, Yarali N
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Semaglutide 2.4 mg for managing overweight and obesity (TA875)
An incidental-finding cohort from a Spanish university hospital (2023) What was found: among 4,800 people who had a B12 measured, about 7 in 100 had a level above 1000 pg/mL
This might seem like an inefficient way to do things, using methylcobalamin just to donate its methyl group and then having to remethylate it