While dihexa at 1 nM and 10 pM alone does not activate c-Met, it markedly augments the capacity of HGF at 1.25 and 2.5 ng/mL to activate c-Met [1]
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The gradual dose escalation, usually at 4-week intervals, helps minimize gastrointestinal adverse effects that commonly occur with GLP-1 receptor agonist therapy
When fluid retention increases, the space becomes tighter, potentially compressing the nerve
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Handling: Let frozen vials warm to room temperature before opening so condensation wont form, and keep the deep-blue solution clear of heat and direct light