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Kinlen D, Cody D, OShea D

doi:10.1111/jocd.13350 Oben, J

Specific compatibility considerations include confirmation of absence of reducing agents for disulphide-containing peptides, BSA carrier supplementation for recombinant proteins, and acetic acid acidification for hydrophobic peptides requiring low pH solubilisation

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Such alterations include incorporating components with reduced anionic charge, which leads to the inability of peptides to aggregate on bacterial membranes and prevents them from entering the cell (Baltzer and Brown, 2011)