Safety and side effects Both forms can cause nausea, vomiting, diarrhea, constipation, bloating, and reduced appetite, especially early in treatment or after dose increases such as moving up from Rybelsus 3 mg [1]
Bracchiglione J et al
Furthermore, we discuss the possible mechanisms involved in the beneficial effects of nutrition on the brain after ES, including neuroinflammation, oxidative stress, hypothalamus-pituitary-adrenal axis regulation and the microbiome-gut-brain axis
These effects have been confirmed in vitro , with some clinical trials still needed to fine tune dosing and therapeutic effects
According to the MHRA-approved Summary of Product Characteristics (SmPC), nausea is very common (affecting more than 1 in 10 people), while abdominal pain, vomiting, diarrhoea, and constipation are common (affecting between 1 in 100 and 1 in 10 people)
This is normal and does not mean you have become dependent on the compound