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The largest analysis to date, presented at the American Society of Nephrologys Kidney Week in 2025, compared roughly 31,000 adults started on semaglutide against a matched group started on metformin
A study using Swedish and Danish national databases compared cancer incidence in over 20,000 GLP-1 users versus other diabetes medications and found no elevated risk for colon or rectal cancers during follow-up periods extending beyond three years
A key effect of semaglutide is reducing appetite
Instead, it may serve as one component of a comprehensive treatment plan designed to support recovery and help patients return to normal activity more comfortably
however, taking recommended painkillers (not NSAIDs), using a heating pad, resting, and sometimes a liquid or bland diet can help if youre recovering at home
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