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This leads to a natural increase in GH and IGF-1 (insulin-like growth factor 1) levels, which promote muscle growth, fat metabolism, and tissue repair

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The four-pathway model therefore targets appetite (GLP-1 and amylin through separate neuronal circuits), fat metabolism (GIP and glucagon), energy expenditure (glucagon primarily), and glucose homeostasis (GLP-1, GIP, and amylin all contribute through different mechanisms)

These models aim to meet the child at his or her development level and use the child's current strengths to build new skills