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1 , e1500447 (2015)

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Additionally, FOXO4-DRI reduced the DHE-positive cell count, indicating decreased ROS levels under OGD conditions (Figure 4F)

As seen in the preclinical results, GSH was at a 4-fold reduction in theT2DM group when compared to the healthy group, therefore supplementing with L-GSH can maintain GSH levels, decrease the levels of oxidized GSH, decrease the levels of the proinflammatory cytokine IL-6 and other oxidative stress markers in individuals with diabetes