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Vriend J, Reiter RJ
Newer drugs like tirzepatide (sold as Zepbound and Mounjaro) combine GLP-1 drugs with glucose-dependent insulinotropic polypeptide (GIP) receptors to increase potency
Adding semaglutide to their treatment plan might not cause the cramps directly, but it may make the problem worse if the underlying nerve damage is not managed well
Changes in the activities of antioxidant enzymes in response to virus infection and hormone treatment
Why it matters: Lillys top rival, Novo Nordisk, also has two very successful GLP-1 drugs (Ozempic and Wegovy) and a third that is less popular, but still brings in over $1 billion in annual US sales (Rybelsus)
doi: 10.1080/17512433.2023.2174099 19 Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group
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