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Just remember that if you have sensitive Skin or allergies, you should always do a patch test before use

Read more: Stopping semaglutide: What to expect and how to prevent weight regain Has anyone stopped semaglutide and kept the weight off

For others, it may persist, requiring ongoing management

But I'd argue the real issue is much more nuanced

Steven Batash, board-certified gastroenterologist and weight-loss expert at Batash Endoscopic Weight Loss, tells PEOPLE

Post-translational modifications, especially those in the DNA binding domain of FOXO4 protein, appear to modify its functionality as a transcription factor and regulation of pathways such as apoptosis, cellular senescence, insulin signaling, and senescence