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In cellular models, 2012 was able to potently and effectively reduce the number of FAK-containing focal adhesions with a sub-micromolar IC 50 value of 0.80 M, which was on par with the K D of 0.8 M at the helix 23 FAT domain site
These processes are central to tissue regeneration
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Anti-inflammatory: 2-4 weeks
Glutamine deprivation triggers NAGK-dependent hexosamine salvage
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