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both these factors may improve brain health and explain the reduced risk of conditions like Alzheimers disease and dementia. While GLP-1RA drugs display effectiveness against a wide array of health problems, the magnitude of associated benefits is modestabout a 10 to 20% reduction for most outcomes
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However, ChAT activity did not correlate with circulating choline or acetylcholine (ACh) concentration, which suggests additional regulatory mechanisms
The early clinical data is suggestive, and the research community continues to investigate their potential applications
Oncotarget 7 , 38323846 (2016)
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