At 1.0 mg (used in STEP 2 as the lower comparison arm), average weight loss was 7.0%
Antimicrob Agents Chemother 57:241247
These results were well predicted by the plasma stability of the hybrids as all the compounds ( 2 , 5 and 9 ) with similar plasma stability to peptide 1 gave comparable results in vivo
Efficacy and safety of once-weekly semaglutide versus sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial
Tirzepatide is commonly discussed as a dual GIP and GLP-1 receptor agonist, while Retatrutide is commonly discussed as a triple GIP, GLP-1 and glucagon receptor agonist
height and weight, but that doesnt tell the whole story, right