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For many individuals, oral B12 supplements are ineffective due to such underlying conditions as: Pernicious anemia : People with this condition lack intrinsic factor, a protein required for B12 absorption in the small intestine
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When people don't get enough of it through their diet, they are prescribed to take a vitamin B complex
(PubMed) Checchi S, Montanaro A, Ciuoli C, et al
Protect from light: B12 in particular is photosensitive
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771
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