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During the propagative phase, molecular oxygen reacts with phospholipid radicals rapidly, leading to the formation of phospholipid peroxy radicals (PLOO)

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Altered expression of 2-integrin, -catenin and genes associated with the Switch/Sucrose Non-Fermentable (SWI/SNF) complex further exacerbate these issues, creating an environment where bladder epithelial cells struggle to regenerate, thereby contributing to the persistent symptoms of IC (Park et al., 2024

GA also inhibits kainate binding present in synaptic plasma membranes, indicating that GA binds to kainate receptor [56]

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