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PMID 28076635
IHC and IF for collected tissue specimens Tissues were collected and incubated for 24 h in 10% buffered formalin and then transferred to 70% ethanol for 2448 h
This isn't just theory
Boehncke WH, Schon MP
We further show that the TRIM37TRIM28 complex, likely acting in cooperation with AP2, restricts chromatin accessibility and H3K27ac levels at somatic gene loci, thereby repressing somatic transcriptional programs in PGCs
The recent advances in high-throughput transcriptomics and metabolic analysis have aided a deeper understanding of macrophage heterogeneity, revealing distinct phenotypes that rely on metabolic pathways involving lactate (Geeraerts et al, 2021), purine (Li et al, 2022), and arginine (Viola et al, 2019)
