showed that a 12-week administration of semaglutide in HFD-induced NAFLD mice reduced body weight, glucose, insulin resistance, LFTs, serum lipids, inflammatory markers [TNF-, interleukin (IL)-6, IL-1], and oxidative stress markers [malonaldehyde (MDA)], thus improving hepatic steatosis, inflammation, mitochondria damage, and fibrosis
This type of medication mimics a natural hormone in the body that helps regulate blood sugar and appetite
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Pharmaceutical companies invest billions in research, development, and clinical trials to bring these drugs to market
Dehydration owing to the potential for GLP-1 and GIP analogues to exacerbate dehydration generally associated with nausea, vomiting and/or diarrhoea
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