amino acids oxidases, cyclooxygenase, lipoxygenase, nitric oxide synthase, xanthine oxidase, NADPH oxidase), oxidative protein folding in the endoplasmic reticulum (ER), the oxidation of free fatty acids (FFAs) in peroxisomes and microsomes, through the effect of pro-inflammatory cytokines, and in the mitochondrial respiratory chain
The current evidence is insufficient to determine whether tirzepatide has any direct effect on erectile function
However, the GI side effects during the transition (particularly vomiting and diarrhea) can cause dehydration, which disproportionately affects people with compromised kidney function
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15,16 These findings suggest that statins may have beneficial effects beyond cholesterol lowering
Pharmacists must recognise that a prescription for 'semaglutide' without specifying the brand could refer to different formulations, and clarification of the intended brand and indication is necessary to prevent medication errors