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The most common adverse effects are gastrointestinal , including nausea, vomiting, diarrhoea, and constipation

10.1523/JNEUROSCI.3442-11.2012 Summary Keywords GLP-1, signaling, diabetes, metabolism, cell function and integrity Citation Rowlands J, Heng J, Newsholme P and Carlessi R (2018) Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function

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Nonetheless, it appears less likely that other receptors modulate the observed effects, as a GLP-1R antagonist (Ex9) blocks the ability of the GLP-1R agonists to exhibit their effects on alcohol drinking (Vallof et al., 2015)