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Humane endpoints were prospectively defined prior to study initiation and included sustained anorexia, marked body weight loss, persistent gastrointestinal disturbances, or other signs of clinical deterioration compromising animal welfare
GLP-1 medications mimic glucagon-like peptide-1, a hormone your body naturally produces to help regulate appetite, digestion, and blood sugar
Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, and decreased appetite, which typically diminish over time as patients develop tolerance to the medication
Adding 2.0mL works but means drawing larger volumes for each dose
Side effects can gradually improve as the body adjusts
(April 2024)
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