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Eat Smaller, More Frequent Meals Eating large meals may overwhelm the digestive system, which can lead to bloating and the production of excess gas

Adjust How You Eat Choose Smaller Portions: Large meals may overwhelm the digestive system when GLP-1 medications slow the movement of food through the stomach

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Zonulin family peptide (zonulin), a potent regulator for intestinal tight junctions, is highly expressed in autoimmune mice and humans and can be used to predict transition from autoimmunity to inflammatory arthritis

Many patients transition to lower maintenance doses or alternative strategies

Its fibres synapse with thalamic neurons