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Multiple studies have shown that NAC supplementation (600-8,000 mg/day) can increase CD4+ T-cell counts, reduce viral load markers, and improve survival in HIV-positive individuals (Herzenberg et al., Proc Natl Acad Sci, 1997) [38]

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Mammalian cell culture Human leukemia (Jurkat and MOLT-4) and kidney epithelial (HEK293T) cell lines were obtained from the American Type Culture Collection

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