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About 10% of patients may experience mild to moderate cognitive adverse effects early on topiramate treatment with verbal fluency being more affected compared to other antiepileptic drugs

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10.1016/s1532-0456(03)00140-6 204 VijayakumarV.SamalS

The structures reveal that lipidation at K10 of peptide 20 allows the hydrophobic acyl tail to interact with the TMD region of all three receptors, providing a fresh clue for peptidic ligand design

Its important to note that these dosages may vary based on individual patient factors, such as weight, age, and overall health status

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