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Stanley TL, Fourman LT, Feldpausch MN, et al

Lactulose to mannitol ratio in humans The ratio of urinary excretion of lactulose to mannitol (LA/MA) was used to measure the intestinal mucosal permeability in ten RA patients and ten healthy controls who underwent colonoscopy, with higher ratios indicative of increased intestinal permeability as previously described 33

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Decreased or lack of absorption due to stomach/bowel issues such as celiac disease, bariatric surgery, Crohn's disease and aging

Journal of Orthopaedic Surgery and Research .Read source (2021)